
Alex J. Antoniou, MD · Physician · Operator · Builder
A physician
who ships.
Twenty years across the bedside, the payer, the boardroom and the terminal. Now I build AI products that turn good habits into better lives.
- 5Products shipped
- 27Books written
- 20+States licensed
- 2×Board certified
Products
Small apps, built to be used daily.
Each one grew out of a problem I was living with. I design, build and ship them myself.





Next: a GLP-1 companion
An AI-supported guide for the whole weight-loss journey on GLP-1 medication, from a physician who prescribes it.
About
Where I come from, and what each part taught me.
For twenty years I have moved between the clinic, the business of healthcare, software and investing, and each one changed the way I saw the others. Here is that story in my own words, with the full record under each part for anyone who wants the details.

01 · Medicine · 2008 – 2016
Medicine
I began in Boston as a biomedical engineer, and on weekends I worked in research labs and on clinical studies. That work led me to medical school, then into the operating room as a surgeon, and then to Johns Hopkins, where I trained in nuclear medicine and cared for patients with cancer. Later I opened a lifestyle and longevity practice over telehealth and wired its systems myself. My patients taught me to lead with empathy. They also taught me that one treatment rarely fits everyone, and that a rule written for everyone can hurt the one patient it was never meant for.
Full record
- MD, Tufts University School of Medicine; BS in biomedical engineering and biology, Tufts, magna cum laude.
- General surgery house staff, UF Shands: 150+ operations across oncology, transplant, vascular and trauma.
- Nuclear medicine house staff and board certification, Johns Hopkins; clinical informatics fellowship, Johns Hopkins.
- Bench and clinical research at Tufts, Boston University, Cedars-Sinai and Hopkins; SNMMI first-place poster, ACNM best oral presentation, JNM top-20 publication.
- Founder, HealthBrew Clinic, a telehealth longevity practice; today Head of Operations at a physician telehealth practice serving all 50 states, in-network with the major payers.

02 · Business · 2016 – 2023
Business
My parents ran their own businesses, so I grew up doing whatever job needed doing that week, from selling and marketing to running operations and moving supplies. Years later a master's in economics taught me how to measure money, and an MBA taught me how to build the systems that move it. I brought both into healthcare, at McKinsey and inside a health plan, where I learned how a decision on paper becomes care for a patient.
Full record
- Chief Medical Officer and Director of Strategy, BlockMedx: drug-monitoring databases and predictive analytics for prescription fraud.
- Designed chronic-disease programs (diabetes, CHF, ASCVD) and chaired quality committees at a Medicare Advantage plan.
- Private-equity diligence on healthcare acquisitions at McKinsey.
- Advisory board, Johns Hopkins Carey Business School; Fellow, Academy for Healthcare Management; Certified in Health Care Quality & Management.

03 · Technology · 2016 – present
Technology
Technology came as a surprise, and it became my second love after medicine. I trained in clinical informatics at Johns Hopkins, earned certificates from MIT, and took part in more than ten hackathons, because I wanted my hobby and parts of my career to run on good software. For the big projects at work I lead teams of engineers and analysts, but on my own time I still build alone, the same way I started.
Full record
- Built, for employers and clients: multiple chronic-disease management verticals, an entire corporate venture and corporate development arm, and a blockchain-based prescription delivery system.
- Clinical informatics fellowship, Johns Hopkins; MIT certificate in AI and machine learning.
- Also maintains uploadcheck-mcp, an MCP server that quality-gates media before an agent publishes it.

04 · Investments · 2007 → 2036
Investments
I learned investing early, when I passed the Series 65 and ran the portfolio for a family office. Since then I have treated every deal as a question of odds, where the real decision is how much to put behind it. Today I manage my own family office with systems I design and test myself, and I built a corporate venture arm that invests in digital health startups.
Full record
- Portfolio manager and Series 65 investment advisor for a family office, 2007–2009.
- Runs a family office today with systematic strategies he designs and tests himself.
- The next decade: back fewer companies, sit closer to the executive decisions, and help them reach the 100× growth that precedes a successful exit.
Writing & open source
Books I have written, and code I give away.
I have written more than twenty books under pen names, most of them to make a hard subject easy to start: how to run a business, how to prepare for the MCAT and USMLE, and a three-volume board review in nuclear medicine. The pen names stay private, but the code I write is public.
Books
Written to be finished in a day.
Open source
Tools I use, shared.
- fable-design-system: an MIT design system that gives AI coding agents real design taste. This site is built with it.
- uploadcheck-mcp: an MCP server that runs 40+ quality gates on a video or audio export before an agent publishes it.
Letters
Occasional notes on medicine, money and machines.
Short essays on medicine, money and machines, and on how AI is changing the work we do with all three.
Letter 01 · October 2026 · 6 min The Last Conversation Why the future of AI is a world where nobody talks to it. Read the letterWhat's next
Looking for the next ten-year problem.
The work I do best sits where medicine, money and software meet. It tends to take one of four shapes.

Build
Start a healthcare AI company from nothing, or the healthcare effort inside a frontier AI lab.

Scale
Help a healthcare company that has found its product grow, as the operator who is also a physician.

Invest
Join as a new partner for the next chapter of AI, where downstream value and profitability matter more than the shiny new use case.

Turn around
Take a healthcare business that has lost its way and put it back on course.
If you are a founder, a board or an investor with a problem like that, I'd like to talk. Partnerships and press reach me at the same address.
Open to the Americas, Europe or the Middle East. Fluent in English, Greek and Arabic.